Learn how different drug tests work, how long THC and other cannabinoids stay in your system, and how to detox quicker to avoid a positive result.
Suffer from a fear of public speaking? You might be encouraged by a new study, which found that CBD can calm nerves in anxiety-inducing situations.
Troy Dayton joins host Kris Krane to talk about the possibility that cannabis giant MedMen could be on the verge of going under, as well as the most recent Congressional hearings on marijuana research and a check in with the latest policy developments in the states. Produced by Shea Gunther.
News & Links:
• 40% of Arizona’s Hemp Crops Must Be Destroyed Due to Too Much THC | AZ Marijuana
• Joe Biden Again Says No To Marijuana Legalization Without More Studies | Marijuana Moment
• Marijuana Sales in 2019 Break a Record… With a Month to Go | Denver Westword
Preliminary research suggests that cannabigerol (CBG) may be the best cannabinoid to utilize in the fight against antibiotic-resistant superbugs like MRSA.
Microbiologists from Hamilton, Ontario’s McMaster University compared CBG against THC (tetrahydrocannabinol) and CBD (cannabidiol) to see which compound was most capable of killing bacteria such as MRSA (methicillin-resistant Staphylococcus aureus). As it turns out, CBG won by a landslide.
Not only did CBG kill the MRSA microbes, but also the remaining “biofilm” that often form on patients’ skin and medical implants. The scientists in this study even went so far as to say CBG was on par with vancomycin, an antiobiotic that so far has the best results in treating drug-resistant bacteria. The study is currently under peer review by the ACS Infectious Diseases journal, but has yet to be certified or published.
Mark Blaskovich, who studies antibiotic
cannabis compounds at the University of Queensland and is reviewing the study, is
optimistic about this new discovery. He noted that cannabis plants are
particularly rich in antimicrobial compounds when compared to other botanicals
such as tea tree, garlic, and turmeric.
“These are likely made as a defense mechanism to protect the plant from bacterial and fungal infections, but to date have not been very useful for human infections as they really only work outside the body,” he said. “That’s what makes this new report potentially exciting – evidence that cannabigerol is able to treat a systemic infection in mice.”
However promising the results are though, it’s
important to remember that we’re only the beginning stages of research. Lead study author Eric Brown
noted that while cannabinoids are “clearly great drug-like compounds, far more
research is necessary before the results can be tested on human patients or
applied in medical settings.”
For more articles like this one, subscribe to the Medical Cannabis Weekly Newsletter.
The post CBG May Be A Leading Defense Against Drug-Resistant Superbugs appeared first on CBD Testers.
Thanks to the 2018 farm bill and
increased awareness of the benefits of using cannabis and hemp, this plant is
once again being grown on a national scale. One of the most important aspects
of this is of course, the rapid rise of public interest in various cannabinoids.
Although CBD and THC lead the way when it comes to cannabis research, another compound is slowly making its way into the spotlight: CBG, or cannabigerol. Although studies on this cannabinoid are limited for the time being, it has enormous therapeutic potential. One of the most recent discoveries slates CBG as a powerful remedy for diminishing certain tumors.
What is CBG?
CBGA was discovered in the 1960s by Israeli Professor, AKA the Father of
Cannabis Research, Raphael Mechoulam and one of his partners, Yehiel Gaoni. As
it turned out, CBGA, the version of CBG that still has its carboxyl acidy group
and can be found in completely raw cannabis plants, is one of the most important
cannabinoids in existence – it’s a precursor to all other cannabinoids. It has
since been rightfully dubbed, the Mother of All Cannabinoids.
Specifically, CBGA (cannabigerolic acid) is a direct line to three main cannabinoids: tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichromenic acid (CBCA). Once exposed to heat or light in process known as decarboxylation, THCA, CBDA, and CBCA will shed their carboxyl acid group and become THC, CBD, and CBC, respectively. When it comes to CBGA though, certain enzymes break it down and it is immediately converted to THCA, CBDA, or CBCA. This is why more THC means less CBG, because of the unique way these compounds interact and are synthesized.
Because of this, plants that do covert to CBG will have their highest cannabigerol content early in the flowering stage. In most cultivars, if left to fully mature, almost all CBG will be converted into other cannabinoids. However, as mentioned above, some hemp strains naturally produce high amounts of CBG rather than CBD or THC.
Anti-Tumor Properties of CBG
A recent press release from Cannabics Pharmaceuticals Inc. announced last week that preliminary findings from their pre-clinical trials conducted in Israel show that CBG has greater anti-tumor effects than CBGA, the acidic from of cannabigerol. Specifically, CBG was found to have an impact on human stomach and bone cancer cell lines.
According to the study, “the HTS platform was utilized to screen the necrotic effects of both CBG & CBGA on various types of cancer cell lines. Interestingly, CBG was found to induce necrotic effects while CBGA had no such effect. These findings further support previous research performed by the company, which has consistently shown differential anti-tumor effects when using a variety of cannabinoids on human cancer cells, derived from both fresh biopsies and cell lines.”
This discovery could
open the door for Cannabics Pharmaceuticals to organize additional research
efforts, as well as eventually offer personalized cannabinoid therapy for patients
in the future.
Dr. Yaakov Waksman, the company’s Head of Cannabidiol Research, had this to say on the subject: “CBG is gaining a lot of interest as of late by the scientific community due to its potential therapeutic properties. The recent preliminary findings from our research team illustrate how purified cannabinoids can potentially yield anti-tumor activity and enable us to examine the entourage effect of botanical extracts versus the purified compounds. We are excited by these preliminary findings and plan to perform additional experiments in the near future to further support them.”
CBG’s Other Benefits
In addition to its anti-tumor
properties, CBG has many other potential medical benefits. Various studies on
this cannabinoid have uncovered its ability to be used as a neuroprotectant, antioxidant, and anti-inflammatory
compound. Limited research also suggests that it can effectively treat
gastrointestinal disorders and glaucoma.
study found CBG to be beneficial in
the treatment of MRSA due to its antibacterial and antifungal properties. Its
neuroprotective properties, mentioned above, may help people with Huntington’s
disease, while further research has looked into its potential to treat bladder
CBG is also being used as a safe and effective
antidepressant and its effects mimic those of SSRI medications. It’s also
believed that CBG can boost production of the endocannabinoid Anandamide, which naturally
increases dopamine levels as well as regulates various functions such as sleep,
mood, and appetite.
How To Find CBG
Although some companies
are already advertising CBG oil for sale, the effectiveness (and safety) of these
products remains to be known. As of now, the most popular way to get your dose
of CBG is through good ole’ fashioned flowers. Although CBG-dominant flowers
are anything but old fashioned, the act of smoking of vaporizing natural
cannabis or hemp buds still remains to go-to method for most consumers.
Because this is a relatively new trend, knowing where to find CBG flowers can be a challenge. Of course, you want to find a company that has good quality buds for a reasonable price. You also want them to be reliable and have good customer service should an issue arise. Multiple hemp flower retailers are selling different CBG strains on their websites, many of which have great reviews, but it can still be difficult to know what is legit and what isn’t in today’s market.
This is why we’ve put together a couple of newsletters to help you find exactly what you’re looking for. If you’re a consumer, we have the CBD Flowers Weekly to bring you deals on all the best hemp flowers. If you’re buying flowers for resale, we’ve created the CBD Flowers Business Newsletter – a weekly subscription that has various pound and wholesale deals.
Subscribe to the newsletter of your choosing and check your email every Thursday morning to learn more about hemp flowers!
For more articles about research and the medical benefits of various cannabinoids, subscribe to the Medical Cannabis Weekly Newsletter.
Researchers just uncovered two new compounds in cannabis. One of them, THCP, may be a game-changer in understanding the plant’s therapeutic potential. Find out why.
The post Meet THCP and CBDP: Study reveals the identification of two new cannabinoids appeared first on Leafly.
The endocannabinoid system (ECS) is a bodily system that works with all other systems to maintain optimal functionality. But did you know that this vital system isn’t covered in medical school?
The post Why isn’t the endocannabinoid system taught in medical schools? appeared first on Leafly.